Ketogenic diet in the treatment of seizures associated with hypothalamic hamartomas
نویسندگان
چکیده
منابع مشابه
Gelastic seizures associated with hypothalamic hamartomas. An update in the clinical presentation, diagnosis and treatment
Gelastic seizures are epileptic events characterized by bouts of laughter. Laughter-like vocalization is usually combined with facial contraction in the form of a smile. Autonomic features such as flushing, tachycardia, and altered respiration are widely recognized. Conscious state may not be impaired, although this is often difficult to asses particularly in young children. Gelastic seizures h...
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Hypothalamic hamartoma (HH) is a benign indolent lesion despite the presentation of refractory epilepsy. Behavioral disturbances and endocrine problems are additional critical symptoms that arise along with HHs. Due to its nature of generating epileptiform discharge and spreading to cortical region, various management strategies have been proposed and combined. Surgical approaches with open cra...
متن کاملEpilepsy syndromes associated with hypothalamic hamartomas
PURPOSE Hypothalamic hamartoma (HH) related epilepsy presents with gelastic seizures (GS), other seizure types and cognitive deterioration. Although seizure origin in GS has been well established, non-GS are poorly characterized. Their relationship with the HH and cognitive deterioration remains poorly understood. We analyzed seizure type, spread pattern in non-GS and their relationship with th...
متن کاملElectrographic Changes Accompanying Recurrent Seizures under Ketogenic Diet Treatment
The ketogenic diet (KD) is increasingly used to treat epilepsy refractory to antiepileptic drugs and other neurological disorders. In animal models, the KD was found to increase the threshold to seizures induced by different convulsive stimulations. However, in models in which suprathreshold stimuli were used, a paradoxical seizure worsening was consistently observed in KD-fed animals. To bette...
متن کاملNeuropsychiatric aspects of patients with hypothalamic hamartomas.
Hypothalamic hamartomas (HH) are developmental malformations that are associated with gelastic seizures, other types of seizures, cognitive decline, and symptoms related to hypothalamic dysfunction. Although aggressive behavior is frequently described, data on the neuropsychiatric profile are limited. In this article, five patients with HH are described who displayed a wide variety of psychiatr...
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ژورنال
عنوان ژورنال: Epilepsy Research
سال: 2011
ISSN: 0920-1211
DOI: 10.1016/j.eplepsyres.2011.02.004